bs-83217C
[Life Science]
GW-501516
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800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
Potent and selective PPARδ (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1 Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves hematopoietic stem cell maintenance.2 Prevents downregulation of AMPK caused by a high-fat diet in liver and increases fatty acid oxidation.3 Upregulates human Sirt1 via Sp1 activation.4 Along with exercise, GW-501516 synergistically increases running endurance.5
Description:
CAS Number: 317318-70-0<br></br>Chemical Name: PPARδ agonist<br></br>Molecular Weight: 453.50<br></br>Formula: C21H18F3NO3S2<br></br>Solubility: DMSO (40 mg/ml) Ethanol (20 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC NMr (Conforms)
Size: 25mg, 5mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.