DATASHEET
Formulation
Tan lyophilized solid
Storage:
-20°C
Product Information:
A novel alkaloid biosynthesized via the roquefortine branched biosynthetic pathway.1,2 Displays excellent ATP-competitive c-MET inhibition, inhibiting the growth, migration and invasion of numerous breast cancer cell lines.3 Also has been shown to inhibit the bacterial enoyl-acyl carrier protein reductase (Fabl) with IC50s in the 33-40 μM range.4
Description:
CAS Number: 71751-77-4; Chemical Name: Met inhibitor; Anticancer activity; Molecular Weight: 433.46; Formula: C23H23N5O4; Solubility: DMSO (10 mg/ml); Physical Properties: Tan lyophilized solid; Purity: 98% by HPLC, NMR (Conforms)