bs-83225C

DATASHEET

Formulation yellow solid

Storage: -20°C

Product Information:

Potent catechol O-methyltransferase (COMT) inhibitor (IC50 = 14.3, 20.1 and 73.3 nM for rat liver soluble COMT, total COMT and membrane-bound COMT respectively).1 Increases bioavailability of L-DOPA as adjunct therapy for Parkinson's disease.2 Inhibits α-synuclein aggregation in vitro and inhibits α-synuclein-induced cell death in PC-12 cells3. Antioxidant. Inhibits oxidative stress-induced cell death4.

Description:

CAS Number: 130929-57-6; Chemical Name: COMT inhibitor - anti-Parkinsons; Molecular Weight: 305.29; Formula: C14H15N3O5; Solubility: DMSO (30 mg/ml) Ethanol (3 mg/ml); Physical Properties: Yellow solid; Purity: 98% by HPLC, NMR (Conforms)

Size: 50mg, 10mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.