bs-83225C
[Life Science]
Entacapone
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support@biossusa.com
800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
Potent catechol O-methyltransferase (COMT) inhibitor (IC50 = 14.3, 20.1 and 73.3 nM for rat liver soluble COMT, total COMT and membrane-bound COMT respectively).1 Increases bioavailability of L-DOPA as adjunct therapy for Parkinson's disease.2 Inhibits α-synuclein aggregation in vitro and inhibits α-synuclein-induced cell death in PC-12 cells3. Antioxidant. Inhibits oxidative stress-induced cell death4.
Description:
CAS Number: 130929-57-6<br></br>Chemical Name: COMT inhibitor - anti-Parkinsons<br></br>Molecular Weight: 305.29<br></br>Formula: C14H15N3O5 <br></br>Solubility: DMSO (30 mg/ml) Ethanol (3 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by HPLC, NMR (Conforms)
Size: 50mg, 10mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.