DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Apicidin is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC’s).1 It also displays antitumor properties by inducing changes in p21WAF1/Cip1 and gelsolin gene expression causing cell cycle arrest in the G1 phase.2 Apicidin dramatically decreases HIF-1α protein levels and transcriptional activity in human and mouse tumor cell lines.3
Description:
CAS Number: 183506-66-3<br></br>Chemical Name: HDAC inhibitor<br></br>Molecular Weight: 623.78<br></br>Formula: C34H49N5O6<br></br>Solubility: DMSO (1 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98%