DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
A cell permeable fungal toxin which binds to the barbed end of actin, inhibiting its polymerization.1 Inhibits cell division, migration and glucose transport.2 Causes cell cycle arrest at G2/M and induces apoptosis in HCT-116 colorectal carcinoma cells.3 Cytochalasin B-induced membrane vesicles (CIMVs) retain cell surface receptors of the parent cells and retain fusion specificity with target cells.4 CIMVs are a promising new vector system for drug and biomolecule delivery due to their natural origin and participation in intercellular communication.5
Description:
CAS Number: 14930-96-2; Chemical Name: Actin filament disrupting agent; Molecular Weight: 479.61; Formula: C29H37NO5; Solubility: DMSO (5 mg/ml) Ethanol (10 mg/ml); Physical Properties: White solid; Purity: 98% by HPLC NMR (Conforms)