bs-83235C

DATASHEET

Formulation Yellow oil or waxy solid

Storage: -20°C

Product Information:

Highly selective nonfluorescent calcium (Ca2+) ionophore.1 Induces a rapid rise in cytosolic Ca2+ in human neutrophils which is due to both release from cytosolic Ca2+ stores as well as Ca2+ influx.2 It activates (2 μM) and primes (20-200 nM) neutrophil NADPH oxidase2. Down regulates beta-catenin/Tcf signaling in a colon cancer cell line via suppressing the binding of Tcf to its specific DNA-binding site.3 In rat hepatoma cells, sub-lethal ionomycin activates the stress response by activating SAPK/JNK and HSF/HSE interaction leading to upregulation of HSP70 biosynthesis.4

Description:

CAS Number: 56092-81-0; Chemical Name: Calcium ionophore; Molecular Weight: 709.01; Formula: C41H72O9; Solubility: DMSO (10 mg/ml) Ethanol (10 mg/ml); Physical Properties: Yellow oil or waxy solid; Purity: 98% by TLC, NMR (Conforms)

Size: 5mg, 1mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.