DATASHEET
Formulation
White or off-white solid
Storage:
-20°C
Product Information:
A dual PI3K and mTOR kinase inhibitor1. It inhibits VEGF-induced proliferation and angiogenesis2. Reverses lapatinib resistance3. It induces G1 arrest and reduces cyclin D1 expression in melanoma cells with negligible apoptosis4. Inhibits the growth of cancer cells with activating PI3K mutations5. Active in vivo.
Description:
CAS Number: 915019-65-7<br></br>Chemical Name: PI 3-K and mTOR inhibitor<br></br>Molecular Weight: 469.55<br></br>Formula: C30H23N5O<br></br>Solubility: DMSO (1 mg/ml) DMF (10 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)