bs-83259C
[Life Science]
Olaparib
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
A highly potent and selective PARP-inhibitor with IC₅₀ values of 5 nM and 1 nM for PARP-1 and PARP-2, respectively.1 In a genetically engineered mouse model for BRCA1-associated breast cancer olaparib inhibited tumor growth and improved survival with no signs of toxicity.2 Synergizes with many other anticancer agents.3 Shows efficacy in colorectal cancers.4 Prevents house dust mite allergen-induced asthma in a mouse model.5
Description:
CAS Number: 763113-22-0<br></br>Chemical Name: PARP1 inhibitor<br></br>Molecular Weight: 434.47<br></br>Formula: C24H23FN4O3 <br></br>Solubility: DMSO (33 mg/ml) Ethanol (1.7 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.