DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
2-Deoxy-D-glucose (2-DG) is a synthetic glucose analog with extensive biological effects. It is commonly thought of as an inhibitor of glycolysis, but its metabolic effects are wide-ranging. 2-DG competitively inhibits glucose uptake via its metabolite 2-Deoxy-D-glucose-6-phosphate, which inhibits hexokinase and phosphoglucose-isomerase leading to decreased ATP production, cell cycle blockage, decreased cell growth and ultimately cell death.1,2
Description:
CAS Number: 154-17-6; Chemical Name: Biologically active glucose analog; Molecular Weight: 164.16; Formula: C6H12O5; Solubility: Water (50 mg/ml)DMSO (15 mg/ml); Physical Properties: White solid; Purity: 98%