DATASHEET
Formulation
Yellow solid
Storage:
-20°C
Product Information:
Potent and selective p38 MAP kinase inhibitor acting at the ATP site1. Selectively inhibits the p38α and β isoforms (IC50= 50 and 100 nM for SAPK2a/p38 and SAPK2b/p38β2 respectively)2. Effectively blocks LPS-induced gene expression in monocytes3. Induces apoptosis4. Cell permeable.
Description:
CAS Number: 152121-30-7<br></br>Chemical Name: p38 MAP kinase inhibitor<br></br>Molecular Weight: 331.35<br></br>Formula: C20H14N3OF<br></br>Solubility: DMSO (30 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by TLC [10% CH3OH in CH2Cl2, Rf = 0.25] NMR (Conforms)