bs-83266C
[Life Science]
SB 203580
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
A potent and selective inhibitor of p38 MAP kinase, IC50=50 and 500 nM for p38 and p38β2 respectively. No other kinases (in a panel of 30) were significantly inhibited including p38γ and δ at 10 μM2. A potent inhibitor of inflammatory cytokine production (IC50=15-25 mg/kg in mice and rats) in animal models of arthritis, bone resorption, endotoxin shock and immune function3.
Description:
CAS Number: 152121-47-6<br></br>Chemical Name: p38 MAP kinase inhibitor<br></br>Molecular Weight: 377.44<br></br>Formula: C21H16N3OSF<br></br>Solubility: DMSO (100 mg/ml) Ethanol (10 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC, NMR (conforms)
Size: 25mg, 5mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.