bs-83266C

DATASHEET

Formulation Off-White solid

Storage: -20°C

Product Information:

A potent and selective inhibitor of p38 MAP kinase, IC50=50 and 500 nM for p38 and p38β2 respectively. No other kinases (in a panel of 30) were significantly inhibited including p38γ and δ at 10 μM2. A potent inhibitor of inflammatory cytokine production (IC50=15-25 mg/kg in mice and rats) in animal models of arthritis, bone resorption, endotoxin shock and immune function3.

Description:

CAS Number: 152121-47-6; Chemical Name: p38 MAP kinase inhibitor; Molecular Weight: 377.44; Formula: C21H16N3OSF; Solubility: DMSO (100 mg/ml) Ethanol (10 mg/ml); Physical Properties: Off-white solid; Purity: 98% by TLC, NMR (conforms)

Size: 25mg, 5mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.