bs-83268C
[Life Science]
Vandetanib
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White or off-white solid
Storage: -20°C
Product Information:
A potent and selective inhibitor of VEGFR2, (KDR IC50 = 40 nM). Also inhibits fms-like tyrosine kinase 4 (VEGFR3, IC50 = 110 nM) and epidermal growth factor receptor (EGFR/HER1, IC50 = 500 nM) but shows selectivity against a panel of other tyrosine and serine-threonine kinases. Inhibits colony formation in seven cancer cell lines2. Displays anti-angiogenesis activity3.
Description:
CAS Number: 443913-73-3<br></br>Chemical Name: VEGFRK inhibitor<br></br>Molecular Weight: 475.35<br></br>Formula: C22H24BrFN4O2<br></br>Solubility: DMSO (30 mg/ml) Ethanol (10 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 50mg, 10mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.