DATASHEET
Formulation
Red Solid
Storage:
-20°C
Product Information:
Displays potent antioxidant and anti-inflammatory activity. Inhibits NFκB (IC50=270 nM). It induces heat shock response and cytoprotection in various cells. Inhibits 20S proteasome chymotrypsin activity (IC50=2.5 μM). Induces autophagy by targeting AR/miR-101 in prostate cancer cells.4 Induces UPR-dependent cell death in cancer cells.5 Cell permeable.
Description:
CAS Number: 34157-83-0; Chemical Name: Proteasome inhibitor; Molecular Weight: 450.62; Formula: C29H38O4; Solubility: DMSO (45 mg/ml) Ethanol (30 mg/ml); Physical Properties: Red Solid; Purity: 98% by TLC, NMR conforms