DATASHEET
Formulation
Red Solid
Storage:
-20°C
Product Information:
Displays potent antioxidant and anti-inflammatory activity. Inhibits NFκB (IC50=270 nM). It induces heat shock response and cytoprotection in various cells. Inhibits 20S proteasome chymotrypsin activity (IC50=2.5 μM). Induces autophagy by targeting AR/miR-101 in prostate cancer cells.4 Induces UPR-dependent cell death in cancer cells.5 Cell permeable.
Description:
CAS Number: 34157-83-0<br></br>Chemical Name: Proteasome inhibitor<br></br>Molecular Weight: 450.62<br></br>Formula: C29H38O4<br></br>Solubility: DMSO (45 mg/ml) Ethanol (30 mg/ml)<br></br>Physical Properties: Red Solid<br></br>Purity: 98% by TLC, NMR conforms