bs-83286C

DATASHEET

Formulation beige solid

Storage: -20°C

Product Information:

Honokiol is a natural product that acts as a SIRT3 activator. It increases mitochondrial oxygen consumption and reduces ROS production in wild type but not SIRT3-KO cells.1 It reversed cardiac hypertrophy in mice1 and rescued myocardial and mitochondrial energetics in type 2 diabetic rats2. It was shown to increase SIRT3 expression in the hippocampus and attenuated surgery-induced memory loss, neuronal apoptosis, neuroinflammation and oxidative damage.3 It increases expression of adipocyte gene markers, gene-involved lipolysis and glucose transport and in general, promotes insulin sensitivity.4

Description:

CAS Number: 35354-74-6; Chemical Name: SIRT3 activator; Molecular Weight: 266.34; Formula: C18H18O2; Solubility: DMSO (50 mg/ml); Physical Properties: Beige solid; Purity: >98% TLC/GC NMR (Conforms)

Size: 50mg, 10mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.