DATASHEET
Formulation
Beige solid
Storage:
-20°C
Product Information:
Honokiol is a natural product that acts as a SIRT3 activator. It increases mitochondrial oxygen consumption and reduces ROS production in wild type but not SIRT3-KO cells.1 It reversed cardiac hypertrophy in mice1 and rescued myocardial and mitochondrial energetics in type 2 diabetic rats2. It was shown to increase SIRT3 expression in the hippocampus and attenuated surgery-induced memory loss, neuronal apoptosis, neuroinflammation and oxidative damage.3 It increases expression of adipocyte gene markers, gene-involved lipolysis and glucose transport and in general, promotes insulin sensitivity.4
Description:
CAS Number: 35354-74-6<br></br>Chemical Name: SIRT3 activator<br></br>Molecular Weight: 266.34<br></br>Formula: C18H18O2<br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: Beige solid<br></br>Purity: >98% TLC/GC
NMR (Conforms)