DATASHEET
Formulation
Orange solid
Storage:
RT
Product Information:
Potent and selective inhibitor of glycogen synthase kinase-1 (GSK-3) IC50=34.3 nM1. Acts at the ATP-binding domain. Displays protective effects in lung fibrosis mouse model2. Displays neuroprotective effects on cultured neurons3. Maintains mouse embryonic stem cells in a pluripotent state4. Cell permeable.
Description:
CAS Number: 280744-09-4; Chemical Name: GSK-3 inhibitor; Molecular Weight: 371.23; Formula: C19H12Cl2N2O2; Solubility: DMSO (25 mg/ml); Physical Properties: Orange solid; Purity: 98% by TLC [1% CH3OH in CH2Cl2; Rf = 0.17] NMR (Conforms)