DATASHEET
Formulation
yellow solid
Storage:
RT
Product Information:
A potent and selective inhibitor of PARP1 and 2. EC50 = 20 nM1. Reduces ischemia reperfusion injury in a mouse model.2 Displays anti-inflammatory effects in a transient focal cerebral ischemia mouse model.3 Causes PARP1 independent, p21 dependent mitotic arrest.4
Description:
CAS Number: 344458-15-7; Chemical Name: PARP1,2 inhibitor; Molecular Weight: 331.81; Formula: C17H17N3O2; Solubility: DMSO (30mg/ml) Water (20 mg/ml); Physical Properties: Yellow solid; Purity: 98% by HPLC NMR (Conforms)