bs-83305C
[Life Science]
Metformin HCl
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: RT
Product Information:
Clinically useful antidiabetic agent. Lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis by activation of the AMP-activated protein kinase (AMPK) pathway.1,2 Displays antiproliferative and pro-apoptotic actions in a variety of cancer cell lines.3,4 Induces autophagy via inhibition of the mTOR pathway. Activates PGC1 and improves mitochondrial dynamics in renal tubular cells.5 Upregulates SIRT1 activity in endothelial cells.6 Neuroprotective and lowers -synuclein phosphorylation in the Parkinson’s disease MPTP mouse model.7
Description:
CAS Number: 1115-70-4<br></br>Chemical Name: Anti-diabetic agent<br></br>Molecular Weight: 165.63<br></br>Formula: C4H11N5 · HCl<br></br>Solubility: DMSO (8 mg/ml) Water (16 mg/ml<br></br>Physical Properties: White solid<br></br>Purity: 98%, NMR (Conforms)
Size: 25g, 5g
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.