bs-83309C [Life Science]
Topotecan HCl
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Formulation yellow solid

Storage: -20°C

Product Information:

Topotecan HCl is a water-soluble and orally active analog of camptothecin, a DNA topoisomerase I inhibitor.1 Inhibits topoisomerase I in human MCF-7 breast and DU-145 prostate cancer cells, IC50s = 13 and 2 nM respectively.2 Downregulates B-Myb and MycN expression in neuroblastoma cells.3 A clinically useful anticancer agent.

Description:

CAS Number: 119413-54-6; Chemical Name: DNA topoisomerase I inhibitor; Molecular Weight: 457.91; Formula: C23H23N3O5 • HCl; Solubility: DMSO (50 mg/ml); water (50 mg/ml); Physical Properties: Yellow solid; Purity: >98% by HPLC NMR (Conforms)

Size: 50mg, 10mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.