DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
Potent and selective inhibitor of MEK1-3. Acts via covalent binding to Cys residue2. In cells, hypothemycin inhibits the MEK-ERK axis with sufficient selectivity to normalize transformed phenotypes3. Inhibits TNFα production in LPS-stimulated macrophages4.
Description:
CAS Number: 76958-67-3; Chemical Name: MEK inhibitor; Molecular Weight: 378.37; Formula: C19H22O8; Solubility: DMSO (10 mg/ml); Physical Properties: White solid; Purity: 98% by HPLC NMR (Conforms)