DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
A 17β-estradiol analog that acts as an estrogen receptor (ER) antagonist and GPR30/GPER agonist with high binding affinity.1,2 First-in-class SERD (selective ER degrader) because it inhibits ER transcriptional activity and leads to its degradation.3 Exhibits mixed neuroprotective activity in vivo.4 Clinically useful option for some advanced breast cancers.5
Description:
CAS Number: 129453-61-8<br></br>Chemical Name: Estrogen receptor antagonist<br></br>Molecular Weight: 606.77<br></br>Formula: C32H47F5O3S<br></br>Solubility: DMSO (60 mg/mL); Ethanol (30 mg/mL)<br></br>Physical Properties: White solid<br></br>Purity: >98% HPLC, NMR (Conforms)