bs-83318C
[Life Science]
Lycorine HCl
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White or off-white solid
Storage: RT
Product Information:
Arrests cell cycle at G2/M phase and induces apoptosis in tumor cells.1 Inhibits human enterovirus 71 replication by blocking elongation of the viral polyprotein during translation and reduces viral cytopathic effects in mice.2 Dose-dependently extends the circadian period length in mammalian cells by enhancing Bmal1 transcription.3 Selectively inhibits human ovarian cancer cell proliferation and neovascularization (IC50=1.2 µM4. A potent SREBF chaperone (SCAP) degrader (Kd=15.24 nM) which acts via an autophagy-independent lysosomal pathway.5
Description:
CAS Number: 2188-68-3<br></br>Chemical Name: Protein synthesis inhibitor/SCAP degrader<br></br>Molecular Weight: 323.77<br></br>Formula: C16H17NO4 • HCl <br></br>Solubility: Water (15 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 50mg,10mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.