bs-83318C

DATASHEET

Formulation white or off-white solid

Storage: RT

Product Information:

Arrests cell cycle at G2/M phase and induces apoptosis in tumor cells.1 Inhibits human enterovirus 71 replication by blocking elongation of the viral polyprotein during translation and reduces viral cytopathic effects in mice.2 Dose-dependently extends the circadian period length in mammalian cells by enhancing Bmal1 transcription.3 Selectively inhibits human ovarian cancer cell proliferation and neovascularization (IC50=1.2 µM4. A potent SREBF chaperone (SCAP) degrader (Kd=15.24 nM) which acts via an autophagy-independent lysosomal pathway.5

Description:

CAS Number: 2188-68-3; Chemical Name: Protein synthesis inhibitor/SCAP degrader; Molecular Weight: 323.77; Formula: C16H17NO4 • HCl; Solubility: Water (15 mg/ml); Physical Properties: White or off-white solid; Purity: 98% by TLC NMR (Conforms)

Size: 50mg, 10mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.