DATASHEET
Formulation
White of off-white solid
Storage:
-20°C
Product Information:
A potent, covalent inhibitor of the NLRP3 inflammasome with anti-inflammatory activity in various mouse models.1 Inhibits vascular inflammation in vivo.2 Inhibits aberrant AKT activation in human breast cancer cells with hyperactivated PI3K/AKT signaling.3 Inhibits migration, invasion and adhesion of melanoma cells.4 Induces apoptosis in osteosarcoma cells by multiple pathways.5
Description:
CAS Number: 28957-04-2; Chemical Name: HSP70 inhibitor; Molecular Weight: 364.43; Formula: C20H28O6; Solubility: DMSO (50 mg/ml) Ethanol (10 mg/ml); Physical Properties: White of off-white solid; Purity: 98% by TLC NMR (conforms)