bs-83321C

DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

A potent and selective inhibitor of c-MET and ALK, IC50s=8 and 20 nM respectively.1 Inhibition of cell proliferation was associated with G1-S phase cell cycle arrest and induction of apoptosis in ALK-positive ALCL cells (IC50=30 nM) but not in ALK-negative lymphoma cells.1 Exhibits cytoreductive antitumor efficacy via antiproliferative and antiangiogenic mechanisms.2 Clinically useful anticancer agent.3

Description:

CAS Number: 877399-52-5; Chemical Name: c-Met and ALK inhibitor; Molecular Weight: 450.34; Formula: C21H22Cl2FN5O; Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml); Physical Properties: White solid; Purity: 98% by HPLC, NMR (Conforms)

Size: 25mg, 5mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.