bs-83337C
[Life Science]
Blebbistatin
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800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
Blebbistatin is a potent, selective, reversible, cell-permeable inhibitor of non-muscle myosin II (IC50 ~4 mM).1,2 During cell division it inhibits contraction of the cleavage furrow without disrupting mitosis.1 Blocks cell blebbing (hence its name) and rapidly disrupts directed cell migration and cytokinesis in many cell types.1 It promotes neurite outgrowth3 and is neuroprotective against vincristine-induced neurotoxicity in iPSC-derived neurons4.
Description:
CAS Number: 674289-55-5<br></br>Chemical Name: Non-muscle myosin II inhibitor<br></br>Molecular Weight: 292.34<br></br>Formula: C18H16N2O2<br></br>Solubility: DMSO (45 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: >98% by TLC NMR (Conforms)
Size: 25mg, 5mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.