bs-83338C

DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

A novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholeretic activity in a rat model of cholestasis.1 Promotes adipocyte differentiation and regulates adipose cell function.2 Normalizes insulin sensitivity in a rabbit model of metabolic syndrome.3 A potentially new therapeutic agent for management of non-alcoholic fatty liver disease4 and NASH5. Displays therapeutic benefit in patients with primary biliary cirrhosis.6 Active in vivo.

Description:

CAS Number: 459789-99-2; Chemical Name: FXR agonist; Molecular Weight: 420.63; Formula: C26H44O4; Solubility: DMSO (35 mg/ml) Ethanol (25 mg/ml); Physical Properties: White solid; Purity: 98% by TLC NMR (Conforms)

Size: 50mg, 10mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.