bs-83338C
[Life Science]
Obeticholic acid
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
A novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholeretic activity in a rat model of cholestasis.1 Promotes adipocyte differentiation and regulates adipose cell function.2 Normalizes insulin sensitivity in a rabbit model of metabolic syndrome.3 A potentially new therapeutic agent for management of non-alcoholic fatty liver disease4 and NASH5. Displays therapeutic benefit in patients with primary biliary cirrhosis.6 Active in vivo.
Description:
CAS Number: 459789-99-2<br></br>Chemical Name: FXR agonist<br></br>Molecular Weight: 420.63<br></br>Formula: C26H44O4<br></br>Solubility: DMSO (35 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 50mg, 10mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.