bs-83348C
[Life Science]
Ophiobolin
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Selectively inhibits the growth of cancer cells (IC50=0.4-4.3 M) over normal cells (IC50=20.9 M).1 Induces non-apoptotic cell death in glioblastoma cells and is active in an in vivo model.2 Covalently reacts with primary amines such as lysine side chains2 and phosphatidylethanolamine3 forming unique pyrrole adducts. Induces ER stress4, paraptosis4 and autophagy5.
Description:
CAS Number: 4611-05-6<br></br>Chemical Name: Autophagy inducer / Anticancer<br></br>Molecular Weight: 400.55<br></br>Formula: C25H36O4 <br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 1mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.