DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
Inhibitor of eukaryotic mevalonate biosynthesis via inhibition of HMG-CoA synthase, IC50=0.12 μM.1 Acts via covalent modification of the active site Cys129.1,2 Inhibits cholesterol biosynthesis in rats (45% at 25 mg/Kg),1 Also inhibits bacterial HMG-CoA synthase.3 Inhibits dengue virus replication.4
Description:
CAS Number: 29066-42-0; Chemical Name: Melvalonate biosynthesis inhibitor; Molecular Weight: 324.41; Formula: C18H28O5; Solubility: DMSO (25 mg/ml); Physical Properties: White solid; Purity: 96% by HPLC NMR (Conforms)