DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Inhibitor of eukaryotic mevalonate biosynthesis via inhibition of HMG-CoA synthase, IC50=0.12 μM.1 Acts via covalent modification of the active site Cys129.1,2 Inhibits cholesterol biosynthesis in rats (45% at 25 mg/Kg),1 Also inhibits bacterial HMG-CoA synthase.3 Inhibits dengue virus replication.4
Description:
CAS Number: 29066-42-0<br></br>Chemical Name: Melvalonate biosynthesis inhibitor<br></br>Molecular Weight: 324.41<br></br>Formula: C18H28O5 <br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 96% by HPLC NMR (Conforms)