DATASHEET
Formulation
White solid/wax
Storage:
-20°C
Product Information:
Teleocidin A1 is a selective protein kinase C activator1 (EC50 = 40 ng/ml) representing a new class of non-phorbol ester tumor promotor2. Teleocidin A1 mimics the effect of diacylglycerol (DAG), activating PKC, but unlike DAG causes persistent activation.3 It enhances actin redistribution, vacuole formation and c-fos expression in PLC/PRF/5 hepatoma cells.4 Occurs in toxic cyanobacterial blooms.5
Description:
CAS Number: 70497-14-2; Chemical Name: Non-phorbol ester PKC activator; Molecular Weight: 437.63; Formula: C27H39N3O2; Solubility: DMSO (15 mg/ml); Physical Properties: White solid/wax; Purity: >95% by HPLC, NMR (Conforms)