bs-83357C

DATASHEET

Formulation Off-White solid

Storage: -20°C

Product Information:

PCI-34051 is a potent and selective HDAC8 inhibitor (IC50=10 nM) with greater than 200-fold selectivity over HDACs 1, 2, 3, 6, 10.1 Unlike broad-spectrum HDAC inhibitors, it does not cause detectable histone or tubulin acetylation.1 Studies employing PCI-34051 showed that HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine.2 It is a very useful tool for exploring the role of HDAC8 in cellular function.3-6

Description:

CAS Number: 950762-95-5; Chemical Name: HDAC8 inhibitor; Molecular Weight: 296.33; Formula: C17H16N2O3; Solubility: DMSO (50 mg/ml); Physical Properties: Off-white solid; Purity: >98% by TLC NMR (Conforms)

Size: 25mg, 5mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.