DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
PCI-34051 is a potent and selective HDAC8 inhibitor (IC50=10 nM) with greater than 200-fold selectivity over HDACs 1, 2, 3, 6, 10.1 Unlike broad-spectrum HDAC inhibitors, it does not cause detectable histone or tubulin acetylation.1 Studies employing PCI-34051 showed that HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine.2 It is a very useful tool for exploring the role of HDAC8 in cellular function.3-6
Description:
CAS Number: 950762-95-5<br></br>Chemical Name: HDAC8 inhibitor<br></br>Molecular Weight: 296.33<br></br>Formula: C17H16N2O3<br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by TLC NMR (Conforms)