DATASHEET
Formulation
Off-White solid
Storage:
-20°C
Product Information:
CBA is a selective blocker of TRPM4 channels (IC50 = 1.5 mM) with no activity at TRPM5, TRPM7, TRPM8, TRPV1, TRPV3, TRPV6 and a panel of other ion channels and receptors.1 Displays protective effects in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration.2 A highly useful tool for exploring the functions of TRM4 in a variety of cell types.3,4
Description:
CAS Number: 351424-20-9; Chemical Name: TRPM4 blocker; Molecular Weight: 340.16; Formula: C15H11Cl2NO4; Solubility: DMSO (35 mg/ml); Physical Properties: Off-white solid; Purity: >98% by TLC NMR (Conforms)