DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Cycloastragenol is a novel naturally occurring terpenoid found in Astragalus which was shown to be a telomerase activator. In CD8+ T lymphocytes from HIV-infected donors it retarded telomere shortening, increased proliferative potential and enhanced cytokine/chemokine production and antiviral activity.1 It suppressed lung damage in a idiopathic pulmonary fibrosis mouse model.2 It has also been shown to be a novel senolytic agent, inducing senescent cell apoptosis and restoring physical function in mice with irradiation-induced aging.3
Description:
CAS Number: 84605-18-5<br></br>Chemical Name: Telomerase activator / Senolytic agent<br></br>Molecular Weight: 490.73<br></br>Formula: C30H50O5<br></br>Solubility: DMSO (60 mg/ml) Ethanol (15 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC NMR (Conforms)