bs-83366C [Life Science]
Lipofermata
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Formulation Off-white solid

Storage: -20°C

Product Information:

Lipofermata is an inhibitor of fatty acid transport protein 2 (FATP2; IC50 = 4.84 µM).1 It does not inhibit glucose transport or the activity of long chain acyl-CoA synthetase. It prevented palmitate-mediated oxidative stress, induction of BiP and CHOP, and cell death in a dose-dependent manner in hsHepG2 and mINS-1E cells suggesting utility in preventing fatty acid-mediated cell death pathways and lipotoxic disease.2 Inhibition was specific for long and very long chain fatty acids but not medium (C6-C10) acids. Lipofermata abrogates lipid transport into melanoma cells and reduces melanoma growth and invasion.3

Description:

CAS Number: 297180-15-5<br></br>Chemical Name: Fatty acid transport protein 2 (FATP2) inhibitor<br></br>Molecular Weight: 360.23<br></br>Formula: C15H10BrN3OS<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98%, NMR (Conforms)

Size: 50mg,10mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.