DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
Anacardic acid is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases p300 and PCAF (IC50’s = 8.5 and 5.0 µM respectively).1 Anacardic acid sensitizes cancer cells to ionizing radiation2 and suppresses proteins involved in invasion and angiogenesis (Src/FAK/Rho GTPases3 and MMP’s 2 (IC50 = 11.11 µM)4 and 9). It inhibits both inducible and constitutive NF-κB activation.5
Description:
CAS Number: 16611-84-0; Chemical Name: HAT inhibitor; Molecular Weight: 348.52; Formula: C22H36O3; Solubility: DMSO (>25 mg/ml) Ethanol (15 mg/ml); Physical Properties: White solid; Purity: 98% by HPLC, NMR (Conforms)