bs-83377C
[Life Science]
RO-3306
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800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-white or pale yellow solid
Storage: -20°C
Product Information:
RO-3306 is a selective inhibitor of CDK1 (IC50 = 35 nM versus CDK2 IC50 = 340nM).1,2 It induces G2/M phase cell cycle arrest and apoptosis. Inhibition of CDK1 with RO-3306 has been shown to have synergistic effects with PARP inhibitors in treating various breast cancers.3,4 It has also been demonstrated to overcome apoptotic resistance in BRAFV600E human colorectal cancer cells.5
Description:
CAS Number: 872573-93-8<br></br>Chemical Name: CDK1 inhibitor<br></br>Molecular Weight: 351.45<br></br>Formula: C18H13N3OS2 <br></br>Solubility: DMSO (15 mg/ml)<br></br>Physical Properties: Off-white or pale yellow solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 25mg,5mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.