bs-83378C [Life Science]
NVS-STG2
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Formulation White solid

Storage: -20°C

Product Information:

NVS-STG2 is a STING agonist that activates human STING by binding in a pocket between the transmembrane domains of neighboring STING dimers in a molecular glue-like manner (AC50 = 5.2 µM). Inactive with mouse STING. NVS-STG2 slowed tumor growth significantly in MC38 tumors inoculated into hSTING knock-in mice.

Description:

CAS Number: 3030588-01-0<br></br>Chemical Name: Molecular glue STING agonist<br></br>Molecular Weight: 427.54<br></br>Formula: C25H33NO5<br></br>Solubility: DMSO (40 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC NMR (Conforms)

Size: 25mg,5mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.