DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
L-755,507 is a very potent (EC50 = 0.43 nM; IC50 = 13 nM) human ß3 adrenergic receptor agonist with >440-fold selectivity of ß1/2.1 It elicited lipolysis and metabolic rate elevation in rhesus monkeys.2 L-755,507 has been shown to increase homology-directed repair efficiency by 2- and 3-fold in CRISPR gene editing.3,4
Description:
CAS Number: 159182-43-1<br></br>Chemical Name: ß3 adrenergic agonist / CRISPR efficiency enhancer<br></br>Molecular Weight: 584.73<br></br>Formula: C30H40N4O6S<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)