DATASHEET
Formulation
beige solid
Storage:
-20°C
Product Information:
SKL2001 is a Wnt/ß-catenin pathway activator that disrupts the Axin/ß-catenin interaction leading to ß-catenin stabilization.1 It suppressed colon cancer spheroid growth via regulation of the E-cadherin/ß-catenin complex.2 A commonly used reagent to reactivate or rescue the Wnt/ß-Catenin signaling pathway.3,4
Description:
CAS Number: 909089-13-0; Chemical Name: Wnt/ß-Catenin pathway activator; Molecular Weight: 286.29; Formula: C14H14N4O3; Solubility: DMSO (>25 mg/ml); Physical Properties: Beige solid; Purity: >98% by HPLC NMR (Conforms)