bs-83383C [Life Science]
XL413·HCl
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Formulation White solid

Storage: -20°C

Product Information:

XL413 is a potent (IC50 = 4.8 nM) ATP-competitive inhibitor of the important DNA replication initiation kinase Cdc7 (DDK).1 It increases the efficiency of homology directed DNA repair in CRISPR-Cas9 gene editing.2 XL413 acted synergistically with other chemotherapy agents in various cancer models.3-5

Description:

CAS Number: 2062200-97-7<br></br>Chemical Name: Cdc7 inhibitor/CRISPR enhancer<br></br>Molecular Weight: 326.18<br></br>Formula: C14H12N3O2·HCl<br></br>Solubility: DMSO (2 mg/ml with warming); water (7 mg/ml with warming)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC NMR (Conforms)

Size: 25mg,5mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.