bs-83383C [Life Science]
XL413·HCl
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

XL413 is a potent (IC50 = 4.8 nM) ATP-competitive inhibitor of the important DNA replication initiation kinase Cdc7 (DDK).1 It increases the efficiency of homology directed DNA repair in CRISPR-Cas9 gene editing.2 XL413 acted synergistically with other chemotherapy agents in various cancer models.3-5

Description:

CAS Number: 2062200-97-7; Chemical Name: Cdc7 inhibitor/CRISPR enhancer; Molecular Weight: 326.18; Formula: C14H12N3O2·HCl; Solubility: DMSO (2 mg/ml with warming); water (7 mg/ml with warming); Physical Properties: White solid; Purity: >98% by HPLC NMR (Conforms)

Size: 25mg, 5mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.