bs-83389C [Life Science]
GS-441524
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Formulation Off-white solid

Storage: -20°C

Product Information:

Parent nucleoside and active metabolite of the SARS-CoV2 drug remdesivir. Displayed broad spectrum antiviral activity against HCV, YFV, DENV-2, influenza A, parainfluenza 3, and SARS-CoV.1 It has been suggested that GS-441524 is superior as an anti-SARS-CoV2 drug due to simplicity of preparation compared to remdesivir, lack of on-target liver toxicity, and the fact that remdesivir is prematurely hydrolyzed to GS-441524 in human serum.2 Additionally, the enzymes that hydrolyze remdesivir to active metabolite GS-441524 are hardly expressed in lungs.

Description:

CAS Number: 1191237-69-0<br></br>Chemical Name: Remdesivir active metabolite<br></br>Molecular Weight: 291.27<br></br>Formula: C12H13N5O4<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)

Size: 50mg,10mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.