bs-83389C

DATASHEET

Formulation Off-White solid

Storage: -20°C

Product Information:

Parent nucleoside and active metabolite of the SARS-CoV2 drug remdesivir. Displayed broad spectrum antiviral activity against HCV, YFV, DENV-2, influenza A, parainfluenza 3, and SARS-CoV.1 It has been suggested that GS-441524 is superior as an anti-SARS-CoV2 drug due to simplicity of preparation compared to remdesivir, lack of on-target liver toxicity, and the fact that remdesivir is prematurely hydrolyzed to GS-441524 in human serum.2 Additionally, the enzymes that hydrolyze remdesivir to active metabolite GS-441524 are hardly expressed in lungs.

Description:

CAS Number: 1191237-69-0; Chemical Name: Remdesivir active metabolite; Molecular Weight: 291.27; Formula: C12H13N5O4; Solubility: DMSO (>25 mg/ml); Physical Properties: Off-white solid; Purity: >98% by HPLC NMR (Conforms)

Size: 50mg, 10mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.