DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Repaglinide is a blocker of the ATP-sensitive potassium channel Kir6 with hypoglycemic activity.1 Clinically useful antidiabetic agent. It displays 30-fold selectivity for pancreatic Kir6.2/SUR1 over cardiac Kir6.1/SUR2B and Kir6/SUR2A channels.2 Repaglinide displayed neuroprotective effects in Huntington disease3, Parkinson’s disease4, and ALS5 via blockade of the DREAM-ATF6 interaction.
Description:
CAS Number: 135062-02-1<br></br>Chemical Name: Kir6 blocker<br></br>Molecular Weight: 453.6<br></br>Formula: C27H36N2O4<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by TLC (NMR Conforms)