DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
Repaglinide is a blocker of the ATP-sensitive potassium channel Kir6 with hypoglycemic activity.1 Clinically useful antidiabetic agent. It displays 30-fold selectivity for pancreatic Kir6.2/SUR1 over cardiac Kir6.1/SUR2B and Kir6/SUR2A channels.2 Repaglinide displayed neuroprotective effects in Huntington disease3, Parkinson’s disease4, and ALS5 via blockade of the DREAM-ATF6 interaction.
Description:
CAS Number: 135062-02-1; Chemical Name: Kir6 blocker; Molecular Weight: 453.6; Formula: C27H36N2O4; Solubility: DMSO (>25 mg/ml); Physical Properties: White solid; Purity: >98% by TLC (NMR Conforms)