bs-83415C

DATASHEET

Formulation Off-White solid

Storage: -20°C

Product Information:

TGX-221 is a potent (IC50 = 5 nM) and selective (1000-fold over p110α and p110γ) inhibitor of PI3-kinase isoform p110ß.1 Displays anti-thrombotic activity without affecting bleeding time.1,2 It significantly inhibited tumorigenesis in VHL, SETD2, PTEN, and CDKN2A mutated clear cell renal cell carcinoma.3 TGX-221 induced apoptosis in glioblastoma cells and inhibited cell migration and invasion.4

Description:

CAS Number: 663619-89-4; Chemical Name: Potent and selective PI3Kß inhibitor; Molecular Weight: 364.45; Formula: C21H24N4O2; Solubility: DMSO (10 mg/ml); Physical Properties: Off-white solid; Purity: 98% by HPLC NMR (Conforms)

Size: 25mg, 5mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.