bs-83418C [Life Science]
Necrosulfonamide
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Formulation Yellow solid

Storage: -20°C

Product Information:

Specifically blocks necroptosis downstream of RIP3 activation by preventing MLKL-RIP3 interaction.1 Displays neuroprotective effects after ischemic brain injury.2 Prevents cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells.3 Binds to gasdermin D inhibiting pyroptosis and associated inflammatory cell death and sepsis.4 Rescues cells from TLR3 ligand-induced death.5

Description:

CAS Number: 1360614-48-7<br></br>Chemical Name: Necroptosis inhibitor / MLKL inhibitor<br></br>Molecular Weight: 461.47<br></br>Formula: C18H15N5O6S2 <br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by HPLC NMR (Conforms)

Size: 25mg,5mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.