bs-83418C

DATASHEET

Formulation yellow solid

Storage: -20°C

Product Information:

Specifically blocks necroptosis downstream of RIP3 activation by preventing MLKL-RIP3 interaction.1 Displays neuroprotective effects after ischemic brain injury.2 Prevents cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells.3 Binds to gasdermin D inhibiting pyroptosis and associated inflammatory cell death and sepsis.4 Rescues cells from TLR3 ligand-induced death.5

Description:

CAS Number: 1360614-48-7; Chemical Name: Necroptosis inhibitor / MLKL inhibitor; Molecular Weight: 461.47; Formula: C18H15N5O6S2; Solubility: DMSO (10 mg/ml); Physical Properties: Yellow solid; Purity: 98% by HPLC NMR (Conforms)

Size: 25mg, 5mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.