DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Asunaprevir is a potent hepatitis C virus NS3 protease inhibitor (IC50 = 0.2 – 3.5 nM).1 Asunaprevir was used as part of a repressible Cas9 system (small molecule-assisted shut off – SMASh) capable of degrading newly synthesized Cas9 protein rapidly to precisely control gene editing.2,3 The Asunapreivr/SMASh system has also been using to target endogenous PD-1 protein for proteasomal degradation.4
Description:
CAS Number: 630420-16-5<br></br>Chemical Name: HCV NS3 protease inhibitor/CRISPR enhancer<br></br>Molecular Weight: 748.29<br></br>Formula: C35H46ClN5O9S<br></br>Solubility: DMSO (>50 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC NMR (Conforms)