bs-83434C
[Life Science]
Ascochlorin
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-White solid
Storage: -20°C
Product Information:
Ascochlorin is a novel isoprenoid phenol isolated from Acremonium egyptiacum and other species.1 It is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex (mitochondrial respiratory chain complex III) acting at both active sites.2 It induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages3 resulting in anti-inflammatory effects4. Demonstrates substantial antineoplastic effects in a variety of tumor cell lines and mouse models.5
Description:
CAS Number: 26166-39-2; Chemical Name: Mitochondrial cytochrome bc1 complex inhibitor; Molecular Weight: 404.93; Formula: C23H29ClO4; Solubility: DMSO (10 mg/ml); Physical Properties: Off-white solid; Purity: >98% by HPLC NMR (Conforms)
Size: 100ug, 500ug
Applications: Life Science(N/A)
For research use only. Not intended for diagnostic or therapeutic use.