bs-83434C [Life Science]
Ascochlorin
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Formulation Off-white solid

Storage: -20°C

Product Information:

Ascochlorin is a novel isoprenoid phenol isolated from Acremonium egyptiacum and other species.1 It is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex (mitochondrial respiratory chain complex III) acting at both active sites.2 It induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages3 resulting in anti-inflammatory effects4. Demonstrates substantial antineoplastic effects in a variety of tumor cell lines and mouse models.5

Description:

CAS Number: 26166-39-2<br></br>Chemical Name: Mitochondrial cytochrome bc1 complex inhibitor<br></br>Molecular Weight: 404.93<br></br>Formula: C23H29ClO4<br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)

Size: 500ug,100ug500ug,100ug

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.