DATASHEET
Formulation
Off-White solid
Storage:
-20°C
Product Information:
AS1842856 potent and selective FOXO1 inhibitor, IC50s=33 nM and >1 mM for FOXO3a and 4.1 Oral administration to diabetic db/db mice leads to a reduction of fasting plasma glucose levels.1 Suppresses autophagy, FSP27 expression and adipocyte differentiation.2 AS1842856 is a highly useful tool for probing the involvement of FOXO1 in cellular processes.3-5
Description:
CAS Number: 836620-48-5; Chemical Name: FOXO1 inhibitor; Molecular Weight: 347.39; Formula: C18H22FN3O3; Solubility: DMSO (10 mg/ml, warm); Physical Properties: Off-white solid; Purity: >98% by HPLC NMR (Conforms)