DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
AS1842856 potent and selective FOXO1 inhibitor, IC50s=33 nM and >1 mM for FOXO3a and 4.1 Oral administration to diabetic db/db mice leads to a reduction of fasting plasma glucose levels.1 Suppresses autophagy, FSP27 expression and adipocyte differentiation.2 AS1842856 is a highly useful tool for probing the involvement of FOXO1 in cellular processes.3-5
Description:
CAS Number: 836620-48-5<br></br>Chemical Name: FOXO1 inhibitor<br></br>Molecular Weight: 347.39<br></br>Formula: C18H22FN3O3<br></br>Solubility: DMSO (10 mg/ml, warm)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)