bs-83440C
[Life Science]
CR8 3HCl (R)
DATASHEET
Formulation White or off-white solid
Storage: -20°C
Product Information:
Second generation analog of roscovitine which inhibits cyclin-dependent kinases with increased potency, Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5, p25, and Cdk9/cyclin T, IC50s=0.09, 0.072, 0.041, 0.11 and 0.18 M respectively.1,2 Acts as a molecular glue degrader that depletes cyclin K.3 CR8 displays neuroprotective effects in various models including traumatic brain injury.4
Description:
CAS Number: 294646-77-8<br></br>Chemical Name: CDK inhibitor<br></br>Molecular Weight: 540.91<br></br>Formula: C24H29N7O ∙3HCl<br></br>Solubility: DMSO (30 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 25mg,5mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.