DATASHEET
Formulation
Off-White solid
Storage:
-20°C
Product Information:
Inhibits constitutive and inducible HSP70 expression in non-stressed1 and heat-stressed2 cancer cells. Blocks the geldanamycin-induced induction of HSP70 and inhibition of TGFß signaling.3 Inhibits leukocyte integrin α4ß7-mediated adhesion of T cells to mucosal addressin cell adhesion molecule 1 (MAdCAM-1) suggesting that HSP70 is essential for ß7 integrin signalling.4 Suppresses morphine analgesic tolerance in a rodent model (100 mg/Kg).5
Description:
CAS Number: 218924-25-5; Chemical Name: Inhibits HSP70 expression; Molecular Weight: 245.23; Formula: C13H11NO4; Solubility: DMSO (30 mg/ml); Physical Properties: Off-white solid; Purity: 98% by HPLC NMR (Conforms)