bs-83441C
[Life Science]
KNK437
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
Inhibits constitutive and inducible HSP70 expression in non-stressed1 and heat-stressed2 cancer cells. Blocks the geldanamycin-induced induction of HSP70 and inhibition of TGFß signaling.3 Inhibits leukocyte integrin α4ß7-mediated adhesion of T cells to mucosal addressin cell adhesion molecule 1 (MAdCAM-1) suggesting that HSP70 is essential for ß7 integrin signalling.4 Suppresses morphine analgesic tolerance in a rodent model (100 mg/Kg).5
Description:
CAS Number: 218924-25-5<br></br>Chemical Name: Inhibits HSP70 expression<br></br>Molecular Weight: 245.23<br></br>Formula: C13H11NO4<br></br>Solubility: DMSO (30 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 25mg,5mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.