bs-83444C
[Life Science]
VE-821
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Beige solid
Storage: -20°C
Product Information:
VE-821 is a potent and selective ATP-competitive ATR (Ataxia-telangiectasia and Rad3-related protein) inhibitor, Ki=13 nM.1 Increases the sensitivity of pancreatic2 and ovarian3 cancer cells to radiation and chemotherapy. Increased replication stress induced by PARP inhibitors or chemotherapeutic agents increases sensitivity to VE-821 in neuroblastoma cells.4 Enhances the cytotoxicity of DNA damaging agents.5
Description:
CAS Number: 1232410-49-9<br></br>Chemical Name: ATR inhibitor<br></br>Molecular Weight: 368.41<br></br>Formula: C18H16N4O3S<br></br>Solubility: DMSO (40 mg/ml)<br></br>Physical Properties: Beige solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 25mg,5mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.