DATASHEET
Formulation
Dark red to light brown solid
Storage:
-20°C
Product Information:
Potent and specific inhibitor of protein kinase C (PKC, IC50 = 50 nM).1 Inhibition of PKC is light dependent2 and is competitive with the diacylglycerol / phorbol ester binding site1. Calphostin C competes with the diacylglycerol / phorbol ester binding site in other proteins such as Munc13-1.3 Reverses oxycodone-induced tolerance to respiratory depression.4
Description:
CAS Number: 121263-19-2; Chemical Name: Protein Kinase C inhibitor; Molecular Weight: 790.77; Formula: C44H38O14; Solubility: DMSO (10 mg/ml); Physical Properties: Dark red to light brown solid; Purity: 98% by HPLC NMR (Conforms)