DATASHEET
Formulation
Off-white to beige solid
Storage:
-20°C
Product Information:
Stimulates human β-cell proliferation both in a dispersed islet proliferation assay and in intact human cultures.1 It has been shown to induce both α- and β-cell proliferation.2 May lead to the development of new therapeutics for diabetes.3 Induces adult hippocampal neurogenesis correlating with its antidepressant effect in a rat model of chronic unpredictable mild stress-induced depression.4 Has been used together with TTNPB and azakenpaullone, as a defined chemical cocktail to induce mouse totipotent stem cells.5 Cell permeable.
Description:
CAS Number: 1421227-53-3; Chemical Name: Stimulates pancreatic beta-cell proliferation; Molecular Weight: 568.6; Formula: C29H31F3N6O3; Solubility: DMSO (30 mg/ml); Physical Properties: Off-white to beige solid; Purity: >98% by HPLC NMR (Conforms)